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1. Introduction
For the application of 1H-NMR spectroscopy to questions
that arise in organic chemistry, it is necessary to be aware of the information
that is contained in NMR spectra. This can be learned with the
help of the two basic approaches that are possible with NMR:
a) Make predictions about the structure of chemical compounds based
on their NMR spectra.
b) Development of hypothetical spectra based on the structure of a
compound.
In this course we will start with the second type of question. As an
example the predicted spectrum (I) of the molecule CH3-CHBr2
is shown that has been derived with the help of the rules described in
this course. It is in very good agreement with the experimental spectrum
(II) of the compound. (Have a good look. This spectrum was recorded
on a continuous wave 60MHz spectrometer, as shown by the wiggles at the
foot of each line. You don't see things like that anymore - Ed.)
Now try to draw the 1H-NMR spectrum of the molecule
below
as a line spectrum. Compare your solution to the actual
spectrum!
Want some help:
What do you have to know to construct an NMR spectrum? When you
have the answer, continue to the next page.
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